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Germacradienol synthase

Part of the Springer Handbook of Enzymes book series (HDBKENZYMES, volume S7)

Keywords

Escherichia Coli Catalytic Activity Hybrid Poplar Cyclization Reaction Product Configuration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Prosser, I.; Altug, I.G.; Phillips, A.L.; Koenig, W.A.; Bouwmeester, H.J.; Beale, M.H.: Enantiospecific (+)-and (−)-germacrene D synthases, cloned from goldenrod, reveal a functionally active variant of the universal isoprenoidbiosynthesis aspartate-rich motif. Arch. Biochem. Biophys., 432, 136–144 (2004)CrossRefPubMedGoogle Scholar
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    Schmidt, C.O.; Bouwmeester, H.J.; Franke, S.; Konig, W.A.: Mechanisms of the biosynthesis of sesquiterpene enantiomers (+)-and (−)-germacrene D in Solidago canadensis. Chirality, 11, 353–362 (1999)CrossRefGoogle Scholar
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    He, X.; Cane, D.E.: Mechanism and stereochemistry of the germacradienol/germacrene D synthase of Streptomyces coelicolor A3(2). J. Am. Chem. Soc., 126, 2678–2679 (2004)CrossRefPubMedGoogle Scholar
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    Luecker, J.; Bowen, P.; Bohlmann, J.: Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (−)-germacrene D synthase and expression of monoand sesquiterpene synthases in grapevine flowers and berries. Phytochemistry, 65, 2649–2659 (2004)CrossRefGoogle Scholar
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    Gust, B.; Challis, G.L.; Fowler, K.; Kieser, T.; Chater, K.F.: PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. Proc. Natl. Acad. Sci. USA, 100, 1541–1546 (2003)CrossRefPubMedGoogle Scholar
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    Cane, D.E.; Watt, R.M.: Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis. Proc. Natl. Acad. Sci. USA, 100, 1547–1551 (2003)CrossRefPubMedGoogle Scholar

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