5-(Carboxyamino)imidazole ribonucleotide mutase

Part of the Springer Handbook of Enzymes book series (HDBKENZYMES, volume S7)


Escherichia Coli Crystal Structure Cell Parameter Ammonium Acetate Energy Requirement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    Meyer, E.; Leonard, N.J.; Bhat, B.; Stubbe, J.; Smith, J.M.: Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway. Biochemistry, 31, 5022–5032 (1992)CrossRefPubMedGoogle Scholar
  2. [2]
    Meyer, E.; Kappock, T.J.; Osuji, C.; Stubbe, J.: Evidence for the Direct Transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase. Biochemistry, 38, 3012–3018 (1999)CrossRefPubMedGoogle Scholar
  3. [3]
    Settembre, E.C.; Chittuluru, J.R.; Mill, C.P.; Kappock, T.J.; Ealick, S.E.: Acidophilic adaptations in the structure of Acetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE). Acta Crystallogr. Sect. D, 60, 1753–1760 (2004)CrossRefGoogle Scholar
  4. [4]
    Mueller, E.J.; Meyer, E.; Rudolph, J.; Davisson, V.J.; Stubbe, J.: N5-carboxyaminoimidazole ribonucleotide: evidence for a new intermediate and two new enzymatic activities in the de novo purine biosynthetic pathway of Escherichia coli. Biochemistry, 33, 2269–2278 (1994)CrossRefPubMedGoogle Scholar
  5. [5]
    Chung, S.O.; Lee, J.H.; Lee, S.Y.; Lee, D.S.: Genomic organization of purK and purE in Brevibacterium ammoniagenes ATCC 6872: purE locus provides a clue for genomic evolution. FEMS Microbiol. Lett., 137, 265–268 (1996)CrossRefPubMedGoogle Scholar
  6. [6]
    Sorensen, I.S.; Dandanell, G.: Identification and sequence analysis of Sulfolobus solfataricus purE and purK genes. FEMS Microbiol. Lett., 154, 173–180 (1997)CrossRefPubMedGoogle Scholar
  7. [7]
    Watanabe, W.; Sampei, G.; Aiba, A.; Mizobuchi, K.: Identification and sequence analysis of Escherichia coli purE and purK genes encoding 5′-phosphoribosyl-5-amino-4-imidazole carboxylase for de novo purine biosynthesis. J. Bacteriol., 171, 198–204 (1989)PubMedGoogle Scholar
  8. [8]
    Schwarzenbacher, R.; Jaroszewski, L.; von Delft, F.; et al.: Crystal structure of a phosphoribosylaminoimidazole mutase PurE from Thermotoga maritima at 1.77 A resolution. Proteins, 55, 474–478 (2004)CrossRefPubMedGoogle Scholar
  9. [9]
    Mathews, I.I.; Kappock, T.J.; Stubbe, J.; Ealick, S.E.: Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway. Structure, 7, 1395–1406 (1999)CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Personalised recommendations