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Ewing Sarcoma/PNET Tumors

  • Chapter
Imaging of Bone Tumors and Tumor-Like Lesions

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Key Points

• ES and PNET are part of the same spectrum of neoplastic disorders, irrespective of their localisation or cellular differentiation.

• ES/PNET occurs in young patients.

• On radiographs/CT, 37.5% are located in the axial skeleton and 62.5% in the peripheral skeleton.

• ES/PNET involving the bone is mostly mixed sclerotic-lytic. A spiculated periosteal reaction is most frequent.

• The most characteristic finding on MRI is the presence of a large soft tissue mass.

• At initial presentation, 20%–30% of patients have pulmonary and/or skeletal metastases.

• PET-CT is becoming standard of care for initial staging, in monitoring response to chemotherapy and detection of recurrence or new metastatic disease.

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Author information

Authors and Affiliations

  1. Department of Radiology, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium

    Filip M. Vanhoenacker, Benjamin Peersman & Arthur M. de Schepper

  2. Department of Radiology, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium

    Filip van Kerkhove & Peter Brys

Authors
  1. Filip M. Vanhoenacker
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  2. Filip van Kerkhove
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  3. Benjamin Peersman
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  4. Peter Brys
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  5. Arthur M. de Schepper
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Editor information

Editors and Affiliations

  1. MRI Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    A. Mark Davies

  2. Section of Musculoskeletal Radiology, Imaging Institute, Diagnostic Radiology/A21, School of Medicine of Case Western Reserve University, Cleveland Clinic Foundation, 9500 Euclid Ave., 44195, Cleveland, OH, USA

    Murali Sundaram

  3. Imaging Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    Steven L. J. James

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© 2009 Springer-Verlag Berlin Heidelberg

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Vanhoenacker, F., van Kerkhove, F., Peersman, B., Brys, P., de Schepper, A. (2009). Ewing Sarcoma/PNET Tumors. In: Davies, A., Sundaram, M., James, S. (eds) Imaging of Bone Tumors and Tumor-Like Lesions. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77984-1_17

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  • DOI: https://doi.org/10.1007/978-3-540-77984-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77982-7

  • Online ISBN: 978-3-540-77984-1

  • eBook Packages: MedicineMedicine (R0)

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