Shock Waves pp 1205-1210 | Cite as

Numerical studies on shock cell interaction

  • X. Y. Hu
  • B. C. Khoo
Conference paper


In this paper, the behavior of a red blood cell under shock impacts has been studied with numerical simulations. Two types of shock wave are considered: one is the planar shock wave and the other is the shock wave induced by bubble collapse. The results show that the bubble induced shock impact is able to cause considerable cell rupture (haemolysis) but the planar shock can only makes several order less strain than the critical value. Furthermore, the roles of the difference viscosity between the blood and cytoplasma seems to play major role for the strain increase after the planar shock passes through the red blood cell.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    M. Delius: Ultrasound Med. Biol. 23, 611 (1997)CrossRefGoogle Scholar
  2. 2.
    X.Y. Hu, B.C. Khoo: ‘A Interface Interaction Method for Compressible Multiphase Flows’. In: Multiphase Flow 2003, November, 3–5, 2003, New Mexico, USA Google Scholar
  3. 3.
    C.W. Huang, T.Y. Shih: Computers & Geosciences 23, 109 (1997)ADSCrossRefGoogle Scholar
  4. 4.
    G.S. Jiang, C.W. Shu: J. Comput. Phys 126, 202 (1996)ADSMathSciNetCrossRefGoogle Scholar
  5. 5.
    M. Lokhandwalla: Damage Mechanisms in Shock Wave Lithotripsy. PhD Thesis, California Institute of Technology, Pasadena, CA (2001)Google Scholar
  6. 6.
    C.W. Shu, S Osher: J. Comput. Phys 77, 439 (1988)ADSMathSciNetCrossRefGoogle Scholar
  7. 7.
    M.A. Stonehill, J.C. Williams et al: Methods Cell Sei. 19, 303 (1998)CrossRefGoogle Scholar
  8. 8.
    J.C. Williams, J.F. Woodward et al: Ultrasound Med. Biol. 25, 1445 (1999)CrossRefGoogle Scholar

Copyright information

© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • X. Y. Hu
    • 1
  • B. C. Khoo
    • 1
  1. 1.Singapore-MIT AllianceSingapore

Personalised recommendations