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External Beam Radiotherapy in the Treatment of Painful Bone Metastases

  • Candice Johnstone
  • Amol J. Ghia
  • Anussara Prayongrat
Chapter

Abstract

The management of bone metastases is a multidisciplinary effort. External beam radiotherapy (EBRT) remains an effective and efficient method by which to palliate pain and prevent pathologic fracture. Various regimens have been utilized in the treatment of bone metastasis. The most commonly used and guideline-supported regimens range from 8 Gy in a single fraction to 30 Gy in 10 fractions. These regimens provide equivalent pain relief with minimal side effects. Stereotactic body radiation therapy (SBRT), a form of high-dose, highly conformal radiation therapy, shows promise in the treatment of selected patients. Due to the expense and complexity, the most appropriate indications for this technology are yet to be determined through continued accrual to ongoing clinical trials. National guidelines and quality metrics help define the use of EBRT in the treatment of uncomplicated bone metastasis.

Keywords

External beam radiotherapy (EBRT) Bone metastases Fractionation Pain Highly conformal therapy Stereotactic body radiation therapy (SBRT) 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Candice Johnstone
    • 1
  • Amol J. Ghia
    • 2
  • Anussara Prayongrat
    • 3
  1. 1.Department of Radiation OncologyMedical College of WisconsinMilwaukeeUSA
  2. 2.University of Texas MD Anderson Cancer Center, Department of Radiation OncologyHoustonUSA
  3. 3.King Chulalongkorn Memorial Hospital and Chulalongkorn University, Department of Radiation OncologyBangkokThailand

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