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Spinal Cord Anatomy

  • David B. Choi
  • Gahie Nam
  • Darren M. Groh
  • Sohail Syed
  • Jared S. Fridley
  • Ziya L. GokaslanEmail author
Chapter

Abstract

The spinal cord begins to form in the second week of gestation, and remains suspended in the spinal canal, surrounded by a column of vertebrae. In adults, the spinal cord spans from the foramen magnum to the conus medullaris, which lies in the thoracolumbar region, while the cauda equina lies in the lumbar spine. Both the cord and cauda equina are encased within the dura mater with a layer of cerebrospinal fluid helping to keep the cord suspended. Dorsal sensory and ventral motor nerve roots, which emanate directly from the cord, combine into a single nerve that exits the spine via the neural foramen.

The interior anatomy of the spinal cord is organized to process both sensory information, as well as to effect motor responses in the trunk and extremities. The internal architecture of the spinal cord reveals a dichotomy of white and gray matter. Within the gray matter, different zones—or nuclei—mediate sensory or motor functions. White matter tracts further relay information as either ascending sensory or descending motor pathways.

Keywords

Spinal cord Anatomy Ascending sensory pathway Descending motor pathway White matter Gray matter Dura mater Cerebrospinal fluid Cauda Equina 

References

  1. 1.
    Sheerin F. Spinal cord injury: anatomy and physiology of the spinal cord. Emerg Nurse. 2004;12(8):30–6.  https://doi.org/10.7748/en2004.12.12.8.30.c1178.CrossRefPubMedGoogle Scholar
  2. 2.
    Wang LL, Bierbrauer KS. Congenital and hereditary diseases of the spinal cord. Semin Ultrasound CT MR. 2017;38(2):105–25.  https://doi.org/10.1053/j.sult.2016.07.002.CrossRefPubMedGoogle Scholar
  3. 3.
    Bui CJ, Tubbs RS, Oakes WJ. Tethered cord syndrome in children: a review. Neurosurg Focus. 2007;23(2):E2.  https://doi.org/10.3171/foc.2007.23.2.2.CrossRefPubMedGoogle Scholar
  4. 4.
    Patel AJ, Relyea K, Fulkerson DH. Embryology of the spine. In: Baaj AA, Mummanei PV, Uribe JS, Vaccaro AR, Greenberg MS, editors. Handbook of spine surgery. New York: Thieme; 2012. p. 3–7.Google Scholar
  5. 5.
    Diaz E, Morales H. Spinal cord anatomy and clinical syndromes. Semin Ultrasound CT MR. 2016;37(5):360–71.  https://doi.org/10.1053/j.sult.2016.05.002.CrossRefPubMedGoogle Scholar
  6. 6.
    Levy RM. Anatomic considerations for spinal cord stimulation. Neuromodulation. 2014;17(Suppl 1):2–11.  https://doi.org/10.1111/ner.12175.CrossRefPubMedGoogle Scholar
  7. 7.
    Gilroy AM, MacPherson BR, Ross LM, Schuenke M, Schulte E, Schumacher U. Atlas of anatomy. 3rd ed. New York: Thieme; 2016.Google Scholar
  8. 8.
    Bartanusz V, Jezova D, Alajajian B, Digicaylioglu M. The blood-spinal cord barrier: morphology and clinical implications. Ann Neurol. 2011;70(2):194–206.  https://doi.org/10.1002/ana.22421.CrossRefPubMedGoogle Scholar
  9. 9.
    Rexed B. The cytoarchitectonic organization of the spinal cord in the cat. J Comp Neurol. 1952;96(3):414–95.CrossRefGoogle Scholar
  10. 10.
    Baba H, Shimoji K, Yoshimura M. Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord (part 1): effects on axon terminals of GABAergic and glycinergic neurons. Anesthesiology. 2000;92(2):473–84.CrossRefGoogle Scholar
  11. 11.
    Slawomirski J, Gluszak J. Structure and topography of the nucleus proprius cornus dorsalis of the spinal cord of horses. Pol Arch Weter. 1986;25(4):131–6.PubMedGoogle Scholar
  12. 12.
    Mannen T. Neuropathological findings of Onuf's nucleus and its significance. Neuropathology. 2000;20(Suppl):S30–3.CrossRefGoogle Scholar
  13. 13.
    Onufrowicz B. Note on the arrangement and function of the cell group in the sacral region of the spinal cord. J Nerv Met Dis. 1899;26:498–504.CrossRefGoogle Scholar
  14. 14.
    Mai JK, Paxinos G. The human nervous system. 3rd ed. Waltham, MA: Academic; 2012.Google Scholar
  15. 15.
    Luria V, Laufer E. Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Dev. 2007;2:13.  https://doi.org/10.1186/1749-8104-2-13.CrossRefPubMedPubMedCentralGoogle Scholar
  16. 16.
    Kamali A, Kramer LA, Butler IJ, Hasan KM. Diffusion tensor tractography of the somatosensory system in the human brainstem: initial findings using high isotropic spatial resolution at 3.0 T. Eur Radiol. 2009;19(6):1480–8.  https://doi.org/10.1007/s00330-009-1305-x.CrossRefPubMedGoogle Scholar
  17. 17.
    Hong JH, Son SM, Jang SH. Identification of spinothalamic tract and its related thalamocortical fibers in human brain. Neurosci Lett. 2010;468(2):102–5.  https://doi.org/10.1016/j.neulet.2009.10.075.CrossRefPubMedGoogle Scholar
  18. 18.
    Siegel A, Sapru HN. Essential neuroscience. 2nd ed. Philadelphia: Lippincott, Williams, & Wilkins; 2010.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • David B. Choi
    • 1
  • Gahie Nam
    • 1
  • Darren M. Groh
    • 1
  • Sohail Syed
    • 1
  • Jared S. Fridley
    • 1
  • Ziya L. Gokaslan
    • 1
    Email author
  1. 1.Department of NeurosurgeryRhode Island Hospital, The Warren Alpert Medical School at Brown UniversityProvidenceUSA

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