Advertisement

Pain pp 285-287 | Cite as

NMDA Receptor Antagonists

  • Carrie Schroeder
  • Kristopher SchroederEmail author
Chapter

Abstract

NMDA receptor antagonists have a number of indications in chronic and acute pain. While ketamine represents the most frequently utilized analgesic from this group, other agents possess similar properties. The use of ketamine has been associated with significantly improved perioperative and chronic pain relief and decreased opioid requirements.

Keywords

Ketamine NMDA Analgesia 

References

  1. 1.
    Petrenko AB, Yamakura T, Baba H, Shimoji K. The role of N-Methyl-D-Aspartate (NMDA) receptors in pain: a review. Anesth Analg. 2003;97:1108–16.CrossRefGoogle Scholar
  2. 2.
    Himmelseher S, Durieux ME. Ketamine for perioperative pain management. Anesthesiolgy. 2005;102:211–20.CrossRefGoogle Scholar
  3. 3.
    Vadivelu N, Schermer E, Kodumudi V, Belani K, Urman R, Kaye A. Role of ketamine for analgesia in adults and children. J Anaesthesiol Clin Pharmacol. 2016;32:298–306.CrossRefGoogle Scholar
  4. 4.
    Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg. 2004;99:482–95.CrossRefGoogle Scholar
  5. 5.
    Suzuki M. Role of N-methyl-D-aspartate receptor antagonists in postoperative pain management. Curr Opin Anaesthesiol. 2009;22:618–22.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Surgical SciencesUniversity of Wisconsin School of Veterinary MedicineMadisonUSA
  2. 2.Department of AnesthesiologyUniversity of Wisconsin School of Medicine and Public HealthMadisonUSA

Personalised recommendations