Quantitative sensory testing (QST) is defined as a broad range of psychophysical methods of stimulation to study somatic sensory physiology, including the perception of pain. It uses an array of tests for evaluating sensory perception during the administration of stimuli with predetermined physical properties and following specific protocols. These stimuli represent specific mechanical (brush, pressure, pinprick, and punctate), thermal (innocuous warm and cold and noxious heat and cold pain), chemical (capsaicin, menthol, histamine), and electrical testing modalities. The response elicited by activation of specific receptors and somatosensory pathways and subsequent activation of small myelinated and unmyelinated fibers and large myelinated fibers. Quantitative information about deficits and positive sensory phenomena specific to each stimulus is obtained.
Depending on the type of stimuli used, QST can assess both small and large fiber dysfunction. It has been used in...
KeywordsQuantitative sensory testing Peripheral neuropathy Neuropathic pain QST Pain testing
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