Neurolytic block therapy is an accepted method of providing sustained analgesia for persistent malignant and non-malignant pain states when conventional treatment strategies have either failed to deliver satisfactory pain control or when prohibitive adverse effects prevent continuation of the conventional therapy. Given the long-term effect of these blocks, strong command of the related anatomy, familiarity with the techniques, and appreciation of potential complications is imperative for successful application of neurolytic block therapy. The focus of this chapter is a discussion of chemical neurolysis with phenol or absolute alcohol for the management of benign and cancer-related pain syndromes.
KeywordsNeurolysis Neural destruction Cancer-related pain Celiac plexus block Superior hypogastric plexus block Lumbar sympathetic plexus block Ganglion impar block Neuraxial neurolytic block
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