Pain pp 495-498 | Cite as

Sciatic Nerve

  • Alaa Abd-Elsayed
  • Jim Eubanks
  • Sherif Zaky


The sciatic nerve is the longest and widest nerve in the human body, coursing from the lumbar spine and buttock down to the lower extremity and foot. It is comprised of spinal nerves L4 to S3 of the sacral plexus, ultimately giving rise to the common peroneal (common fibular) nerve and tibial nerve. Due to its size, length and course, it plays an important role in clinical conditions including spinal stenosis and disc herniation associated with radiculopathy, also known as sciatica. Conservative management is first line therapy, with surgical intervention reserved for recalcitrant or complicated cases. Nerve blocks can play an important role in providing symptomatic relief.


Common peroneal nerve Common fibular nerve Tibial nerve Sciatic nerve Sciatica Lumbar radiculopathy Nerve entrapment Foot drop Surgical release 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Alaa Abd-Elsayed
    • 1
  • Jim Eubanks
    • 2
  • Sherif Zaky
    • 3
    • 4
  1. 1.Department of AnesthesiologyUniversity of Wisconsin School of Medicine and Public HealthMadisonUSA
  2. 2.Department of Physical Medicine and RehabilitationBrody School of Medicine at East Carolina UniversityGreenvilleUSA
  3. 3.Firelands Regional Medical CenterSanduskyUSA
  4. 4.Ohio Heritage UniversityWestlakeUSA

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