Resources for Modeling in Computational Neuroscience

  • Justas Birgiolas
  • Sharon M. Crook
  • Richard C. GerkinEmail author
Part of the Springer Series in Computational Neuroscience book series (NEUROSCI)


Computational models of the nervous system help researchers discover principles of brain operation and form/function relationships. They can provide a framework for understanding empirical data and serve as an experimental platform to test concepts and intuitions. In practice, the effective use of theoretical, computational, and information theoretic approaches requires an ongoing cycle of experiments, data analysis, modeling studies, and model-generated predictions that are tested by further empirical work. This cycle requires that computational scientists be able to build on the work of others. In this chapter, we provide an overview of simulation tools and resources for creating computational models of hippocampal function. First, we outline some of the most widely used software applications for simulating models at various levels of biological detail. We also describe resources that aid in reproducibility by allowing for model sharing and reuse, for portability of models across simulation platforms, and for validation of models against experimental data.


Model reproducibility Simulation software Model validation Data-driven models Model sharing 



This work was supported in part by the National Institute on Deafness and Other Communication Disorders and the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health under award numbers 1F31DC016811 to JB and R01MH106674 to SMC and R01EB021711 to RCG. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Justas Birgiolas
    • 1
  • Sharon M. Crook
    • 2
  • Richard C. Gerkin
    • 1
    Email author
  1. 1.School of Life SciencesArizona State UniversityTempeUSA
  2. 2.School of Mathematical and Statistical Sciences, School of Life SciencesArizona State UniversityTempeUSA

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