Equipment and Instrumentation for Radiopharmaceutical Chemistry

  • Stephen Thompson
  • Peter J. H. ScottEmail author


Radiochemistry facilities in both academic medical centers and commercial nuclear pharmacies consist of technologically advanced laboratories paired with sophisticated imaging and data analysis suites. These units are staffed by multidisciplinary teams of basic scientists, clinicians, technologists, staff scientists, and students and are equipped with state-of-the-art instruments for the daily production of radiopharmaceuticals as well as the performance of preclinical and clinical nuclear imaging and targeted radiotherapy experiments. In this chapter, we will use the lens of positron emission tomography (PET) to provide an overview of the major instrumentation and equipment needed to take a radiopharmaceutical from bench-to-bedside in a manner that is compliant with all pertinent regulations. We also turn our eyes to the future, imagining what the PET Center of tomorrow will look like once all the equipment is connected through the Internet of Things (IoT).


Positron emission tomography, PET, radiochemistry Automation Miniaturized quality control Internet of Things 



Financial support of this work from the US DOE (DE-SC0012484) is gratefully acknowledged. The authors declare no competing financial interest.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of RadiologyUniversity of MichiganAnn ArborUSA

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