Although the differential for hypercalcemia in the surgical patient is broad, a stepwise approach to the diagnosis and management will ensure adequate management of this common electrolyte abnormality. Hyperparathyroidism and malignancy account for 90% of hypercalcemic patients. Treatment is largely etiology specific and may be altered based on the presence or absence of associated symptoms.
Calcium Electrolyte abnormalities Hypercalcemia Hyperparathyroidism Parathyroid hormone Vitamin D
This is a preview of subscription content, log in to check access.
Lafferty FW. Differential diagnosis of hypercalcemia. J Bone Miner Res. 1991;6(S2):S51–9.CrossRefGoogle Scholar
Ratcliffe WA, et al. Role of assays for parathyroid-hormone-related protein in investigation of hypercalcemia. Lancet. 1992;339(8786):164–7.CrossRefGoogle Scholar
Koo WS, et al. Calcium-free hemodialysis for the management of hypercalcemia. Nephron. 1996;72(3):424.CrossRefGoogle Scholar
Sandler LM, et al. Studies of the hypercalcemia of sarcoidosis: effect of steroids and exogenous vitamin D3 on the circulating concentrations of 1,25-dihydroxy vitamin D3. Q J Med. 1984;53(210):165–80.PubMedGoogle Scholar