Acute pancreatitis is one of the most common gastrointestinal disorders requiring hospitalization. Approximately 20% of pancreatitis patients will develop pancreatic necrosis, which can lead to a systemic inflammatory response, multi-organ system failure, and death. Early intervention is essential to avoid poor outcomes. Open necrosectomy has historically been the treatment of choice. More recently, a step-up approach has become more common. This chapter discusses this approach, which is depicted in the subsequent algorithm.
KeywordsAcute pancreatitis Pancreatic necrosis Necrosectomy Step-up approach Algorithm
- 5.Working Group IAPAPAAPG. IAP/APA evidence-based guidelines for the management of acute pancreatitis. Pancreatology. 2013;13(4 Suppl 2):e1–15.Google Scholar