When Should a Non-gastrointestinal Cause of Nausea and Vomiting Be Considered?

  • Kraftin E. SchreyerEmail author
  • Deena D. Wasserman
  • Evan Kingsley


Nausea and vomiting are symptoms present in many disease processes. Unfortunately, the lack of specificity of these symptoms means that their presence does not rule in or rule out any specific etiology. The clinician must conduct a thorough history and physical exam in an attempt to determine whether a cause outside of the gastrointestinal system should be considered. The history and physical are the best tools to guide further diagnostic testing and may frequently lead to the ultimate diagnosis in patient with nausea and vomiting.


Nausea Vomiting History Diagnosis Non-gastrointestinal vomiting 


  1. 1.
    Agency for Healthcare Research and Quality: Healthcare Cost and Utilization Project. HCUPnet – Emergency Department National Statistics, 2014 National Diagnoses--ICD-9-CM Codes (ICD9), Principal Diagnosis: 787.01 Nausea With Vomiting (after Oct 1, 2009) [Internet]. 2017 [cited 16 Aug 2017]; Available from:
  2. 2.
    Anderson WD, Strayer SM. Evaluation of nausea and vomiting: a case based approach. Am Fam Physician. 2013;88:371–9.PubMedGoogle Scholar
  3. 3.
    Harbord M. Nausea and vomiting. Medicine. 2009;37:115–8.CrossRefGoogle Scholar
  4. 4.
    Scorza K, Williams A. Evaluation of nausea and vomiting. Am Fam Physician. 2007;76:76–84.PubMedGoogle Scholar
  5. 5.
    Hasler W, Chey W. Nausea and vomiting. Gastroenterology. 2003;125:1860–7.CrossRefGoogle Scholar
  6. 6.
    Quigley E, Hasler W, Parkman H. AGA technical review on nausea and vomiting. Gastroenterology. 2001;120:263–86.CrossRefGoogle Scholar
  7. 7.
    Metz A, Hebbard G. Evaluation of nausea and vomiting in adults: a diagnostic approach. Aust Fam Physician. 2007;36:688–92.PubMedGoogle Scholar
  8. 8.
    Batchelor J, McGuiness A. A meta-analysis of GCS 15 head injured patients with loss of consciousness or post-traumatic amnesia. Emerg Med J. 2002;19:515–9.CrossRefGoogle Scholar
  9. 9.
    Hall J, Driscoll P. Nausea, vomiting and fever. Emerg Med J. 2005;22:200–4.CrossRefGoogle Scholar
  10. 10.
    American Gastroenterological Association medical position statement. Nausea and vomiting. Gastroenterology. 2001;120:261–2.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Kraftin E. Schreyer
    • 1
    Email author
  • Deena D. Wasserman
    • 1
  • Evan Kingsley
    • 1
  1. 1.Department of Emergency MedicineTemple University HospitalPhiladelphiaUSA

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