What Are the Best Management Strategies for Hyperemesis Gravidarum?

  • Lindsey DeGeorge
  • Lauren Wiesner


Hyperemesis gravidarum (HG) is characterized by unrelenting nausea and vomiting in pregnancy and may be accompanied by weight loss, electrolyte abnormalities, and dehydration. Prompt recognition and early efforts to control symptoms are essential to limiting progression of disease. Fluid and electrolyte repletion, as well as pharmacologic control of symptoms, is the mainstay of acute HG management. Pharmacologic therapy includes dopamine antagonists, selective serotonin inhibitors, and H1 antagonists. For patients with prolonged symptoms, treatment should include supplemental folate and thiamine. Admission is reserved for patients with significant electrolyte abnormalities or severe symptoms refractory to pharmacologic intervention.


Hyperemesis gravidarum Vomiting Nausea Pregnancy Dehydration Ondansetron 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Lindsey DeGeorge
    • 1
  • Lauren Wiesner
    • 2
    • 3
  1. 1.Department of Emergency MedicineMedStar Washington Hospital CenterWashington, DCUSA
  2. 2.Georgetown University School of Medicine, Department of Emergency MedicineWashington, DCUSA
  3. 3.MedStar Washington Hospital CenterWashington, DCUSA

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