Healing of Myocardial Infarction

  • Nikolaos Papageorgiou
  • Dimitris Tousoulis


Myocardial infarction (MI) and the resulting loss of functionality of the myocardium appear to be the major causes for the failing heart. Despite aggressive therapeutic strategies, prognosis remains poor in patients with big infarction and severe left ventricular dysfunction. Therefore, it appears of great importance to enhance myocardial healing aiming to preserve its structure and function. Underlying processes as well as general known healing factors appear to be essential for myocardial healing. Their role and the available therapeutic approaches will be discussed in the present chapter.


Healing Myocardial infarction Cardioprotection Inflammation Fibrosis Remodelling Reperfusion Risk factors Biomarkers Apoptosis mRNA 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Nikolaos Papageorgiou
    • 1
    • 2
  • Dimitris Tousoulis
    • 2
  1. 1.Electrophysiology DepartmentBarts Heart Centre, St. Bartholomew’s HospitalLondonUK
  2. 2.1st Cardiology DepartmentHippokration Hospital, Athens University Medical SchoolAthensGreece

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