Unlike other microscopic lesions, villous oedema is often a descriptive, not a diagnostic, term. It is characterised by an accumulation of fluid in the villous stroma and between capillaries and the trophoblast layer. Diffuse villous stromal oedema may indicate fetal hydrops (immune/non-immune), but histologic assessment is often unable to establish an underlying diagnosis. Patchy or focal villous oedema may be insignificant or may be seen in association with established regional flow changes in the fetal circulation.
KeywordsHydrops Villous oedema Oedema Chorioamnionitis Fetal vascular malperfusion
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