Management of Frontal Sinus Malignancy

  • Aykut A. Unsal
  • Suat Kilic
  • Peter F. Svider
  • Jean Anderson Eloy


Frontal sinus malignancies are rare tumors that typically present at advanced stages with nonspecific signs and symptoms such as nasal obstruction, epistaxis, headache, facial pain, and hyposmia/anosmia. They are more common in men and tend to present in the seventh decade of life. The most common histologies are squamous cell carcinoma, diffuse large B-cell lymphoma, and adenocarcinoma. They are usually managed with surgical resection and postoperative radiotherapy. Traditionally, tumor resection has been performed via open methods. More recently, endoscopic endonasal techniques have been reported with some success in treating these malignancies. Despite these advances, prognosis remains poor.


Frontal sinus malignancy Frontal sinus cancer Sinus cancer Sinus malignancy Frontal sinus surgery 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Aykut A. Unsal
    • 1
  • Suat Kilic
    • 2
  • Peter F. Svider
    • 3
  • Jean Anderson Eloy
    • 2
    • 4
    • 5
    • 6
  1. 1.Department of Otolaryngology – Head and Neck SurgeryMedical College of Georgia – Augusta UniversityAugustaUSA
  2. 2.Department of Otolaryngology – Head and Neck SurgeryRutgers New Jersey Medical SchoolNewarkUSA
  3. 3.Department of Otolaryngology – Head and Neck SurgeryWayne State University School of MedicineDetroitUSA
  4. 4.Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical SchoolNewarkUSA
  5. 5.Department of Neurological SurgeryRutgers New Jersey Medical SchoolNewarkUSA
  6. 6.Department of Ophthalmology and Visual ScienceRutgers New Jersey Medical SchoolNewarkUSA

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