Frontal Sinus Inverted Papilloma: Unique Considerations

  • Vidur Bhalla
  • Alexander Chiu
  • D. David Beahm


Schneiderian papillomas are sinonasal, benign neoplasms of the mucosa consisting of squamous or columnar epithelium. Several types of papillomas exist in the sinonasal cavity, most commonly exophytic (fungiform), cylindrical (oncocytic), and inverted. Inverted papillomas (IPs) are named for squamous metaplasia that histologically expands inward toward the stroma. Males are more frequently affected than women at a 3.4:1 ratio. The average age of presentation is in the mid-50s. IP is thought to arise from a single progenitor cell. The etiology is unknown. Viruses including EBV and HPV are thought to play a role in all papilloma types, including IP; however, not all specimens demonstrate positivity. HPV is present in approximately 38% of IPs. Surgical resection is the treatment of choice.


Schneiderian papillomas Krouse Cannady Endoscopic modified Lothrop Frontal sinus outflow tract 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Vidur Bhalla
    • 1
  • Alexander Chiu
    • 1
  • D. David Beahm
    • 1
  1. 1.University of Kansas Medical Center, Department of Otolaryngology – Head and Neck SurgeryKansas CityUSA

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