Engineered Nanoparticles: Are They an Inestimable Achievement or a Health and Environmental Concern?
Inorganic particles often exhibit novel and outstanding properties as their size approaches nanosize dimensions. The synthesis of these nanoengineered materials with specific composition, architecture, and functionality, and their uses in diverse fields, are changing paradigms. In this chapter we highlight the application of a lot of nanoparticles in biology, medicine, and biomedical engineering, and some concerns regarding human and environmental health are also discussed. There are two approaches to nanoparticle development and application for health care purposes: the bottom-up (science-driven) approach and the top-down (regulation-driven) approach, but neither of these has been able to demonstrate health care benefits without toxicological side effects. Consequently, nanoparticle toxicity has to be assessed, and the standardization of techniques should be set by scientists and decision makers worldwide. Cutting-edge knowledge regarding the interactions between nanoparticles and human health has to move forward, but environmental quality and social welfare must also be ensured.
KeywordsBiocompatibility and toxicity Current challenge Drug delivery Environment pollution Human disease Modern medicine Molecular diagnostics Sustainable development
This research was founded by ‘Ciencia Básica SEP-CONACyT’ projects 151881 and 287225, the Sustainability of Natural Resources and Energy Programs (Cinvestav-Saltillo), and Cinvestav Zacatenco. L-S S received grantaided support from ‘Becas Conacyt’. F-L F and L-V F received grant-aided support from ‘Sistema Nacional de Investigadores (SNI)’, México.
Competing Interests The authors declare that they have not competing interests.
- Alivisatos P, Cummings P, DeYoreo J, Fichthorn K, Gates B, Hwang R, Lowndes D, Majumdar A, Makowksi L, Michalske T, Misewich J, Murry C, Sibener S, Teague C, Williams E (2005) Nanoscience research for energy needs: report of the March 2004 National Nanotechnology Initiative Grand Challenge Workshop. Energy 86Google Scholar
- Conserve Energy Future (2017) Pollution facts. http://www.conserve-energy-future.com/various-pollution-facts.php. (Verified December 18, 2017).
- Fernández-Luqueño F, López-Valdez F, Valerio-Rodríguez MF, Pariona N, Hernández-López JL, García-Ortíz I, López-Baltazar J, Vega-Sánchez MC, Espinosa-Zapata R, Acosta-Gallegos JA (2014) Effects of nanofertilizers on plant growth and development, and their interrelationship with the environmental. In: López-Valdez F, Fernández-Luqueño F (eds) Fertilizers: components, uses in agriculture and environmental impact. NOVA Science, New York, pp 211–224Google Scholar
- Fonseca-Santos B, Gremiao MPD, Chorilli M (2015) Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease. Int J Nanomed 10:S87148Google Scholar
- Kulinowski K, Lippy B (2011) Training workers on risks of nanotechnology. National Clearinghouse for Worker Safety and Health Training, National Institute of Environmental and Health Sciences, Research Triangle ParkGoogle Scholar
- Liu J, Jiang G (2015) Silver nanoparticles in the environment, 1st edn. Springer-Verlag Berlin, Heidelberg, pp 1–152Google Scholar
- Liu Y, Sun Y, Zeng F, Xie W, Liu Y, Geng L (2014) Effect of nano SiO2 particles on the morphology and mechanical properties of POSS nanocomposite dental resins. J Nanopart Res 16:1–8Google Scholar
- Logothetidis S (2012) Nanotechnology: principles and applications. Nanosci Technol 59:1–22Google Scholar
- Mantovani E, Borsella E, Porcari A (2016) Nanotechnologies: opportunities and challenges. Gior Ital Dermat V 38:158–160Google Scholar
- Mishnaevsky L, Levashov E, Valiev RZ, Segurado J, Sabirov I, Enikeev N, Prokoshkin S, Solov’Yov AV, Korotitskiy A, Gutmanas E, Gotman I, Rabkin E, Psakh’E S, Dluhoš L, Seefeldt M, Smolin A (2014) Nanostructured titanium-based materials for medical implants: modeling and development. Mater Sci Eng R Rep 81:1–19CrossRefGoogle Scholar
- Mohapatra M, Anand S (2010) Synthesis and applications of nano-structured iron oxides/hydroxides—a review. Int J Eng Sci Technol 2:127–146Google Scholar
- Ogunlusi GO, Adekunle AS, Maxakato NW, Mamba BB (2012) Characterization of a nano-synthesised cobalt complex and its electrocatalytic properties towards nitrite oxidation. Int J Electrochem Sci 7:2904–2917Google Scholar
- Panyala NR, Peña-Méndez EM, Havel J (2009) Gold and nano-gold in medicine: overview, toxicology and perspectives. J Appl Biomed 7:75–91Google Scholar
- Rutnakornpituk M, Baranauskas VV, Riffle JS, Connolly J, Pierre TGS, Dailey JP (2002) Polysiloxane fluid dispersions of cobalt nanoparticles in silica spheres for use in ophthalmic applications. Eur Cells Mater 3:102–105Google Scholar
- Samimi A, Zarinabadi S (2012) Reduction of greenhouse gases emission and effect on environment. Am J Sci 8:1011–1015Google Scholar
- Vatta LL, Sanderson RD, Koch KR (2006) Magnetic nanoparticles: properties and potential applications. Adv Mater 78:1793–1801Google Scholar