Medical Management of GERD

  • Feng Li
  • Stephanie Denise Pointer
  • Jon P. WalkerEmail author


Nonsurgical approaches continue to be at the cornerstone for initial therapy of GERD. Ultimately, the most efficacious therapy depends on the etiology of GERD symptoms. Therapies range from acid suppression with proton pump inhibitors to baclofen for non-acid reflux to neuromodulators for functional heartburn. While PPI therapy is very safe, it is important to understand the reported potential pitfalls of long-term use. The prescriber must also understand the risks and benefits of GERD therapy in the pregnant or breastfeeding patient. This chapter presents an overview of the therapeutic options available to the managing provider.


Proton pump inhibitor H2 blocker GERD Non-acid reflux Functional heartburn 


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Copyright information

© SAGES 2019

Authors and Affiliations

  • Feng Li
    • 1
  • Stephanie Denise Pointer
    • 1
  • Jon P. Walker
    • 1
    Email author
  1. 1.Division of Gastroenterology, Hepatology, and NutritionThe Ohio State University Wexler Medical CenterColumbusUSA

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