A Movement toward Precision Medicine in Acute Brain Injury: The Role of the Cerebral Venous System

  • Jinqi Luo
  • Sheng Chen
  • Cesar Reis
  • Jianmin ZhangEmail author
Part of the Springer Series in Translational Stroke Research book series (SSTSR)


Worldwide, there is a strong emphasis placed on precision medicine. It is defined as an entire system including preclinical research, diagnostic technology, treatment, as well as prognosis and prevention. In terms of central nervous system diseases, especially those involving vascular malfunction, efficacious preventions and treatments depend on precise early diagnosis and personalized therapeutic protocols. In this chapter, we discuss the role of the central venous system in precision medicine for acute brain injury. We cover aspects of molecular mechanisms, molecular and radiological diagnosis, and personal treatments. Precision medicine integrates scattered medical information into a relevant and useful system aimed at developing individualized therapy for every patient to optimize efficacy and prognosis. Precision medicine is a new and complex initiative in the medical community, and with regards to central venous system disorders, individualized treatment will require ongoing research and development to achieve optimal efficiency and use.


Precision medicine Acute brain injury Central venous system 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Jinqi Luo
    • 1
    • 2
    • 3
  • Sheng Chen
    • 1
    • 2
    • 3
  • Cesar Reis
    • 4
  • Jianmin Zhang
    • 1
    • 2
    • 3
    Email author
  1. 1.Department of NeurosurgerySecond Affiliated Hospital, School of Medicine, Zhejiang UniversityHangzhouChina
  2. 2.Brain Research Institute, Zhejiang UniversityHangzhouChina
  3. 3.Collaborative Innovation Center for Brain ScienceZhejiang UniversityHangzhouChina
  4. 4.Department of Preventive MedicineLoma Linda University Medical CenterLoma LindaUSA

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