Role of Cerebral Venous System in Traumatic Brain Injury
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Traumatic brain injury (TBI) is one of the most prevalent causes of neurological dysfunction, leading to substantial economic and social burdens worldwide. The brain edema, including cytotoxic and vascular brain edema, is one of the most important hallmarks of TBI. Brain edema induces an increase in intracranial pressure (ICP), resulting in decreased cerebral vascular perfusion and cerebral ischemia. In recent years, studies have suggested that the balance between the arterial blood inflow and venous output is crucial for brain homeostasis. However, the role of cerebral venous system in vascular brain edema has always been overlooked and remains unclear. In this chapter, we are going to discuss about the role of cerebral venous system in TBI and provide some theoretical evidence for the clinical management of TBI.
KeywordsTraumatic brain injury (TBI) Cerebral venous system Brain edema
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