Hypotonia in the Newborn

  • Ranjith KamityEmail author


This chapter discusses the clinical approach to a newborn presenting with hypotonia in the newborn nursery. Various etiologies are discussed using a step-by-step approach to ruling out the differential diagnoses in a question-based format. The discussion is aimed at the nursery provider and provides an algorithmic approach to diagnosing the most common etiologies that can present with hypotonia in a newborn. A brief discussion of systemic causes of hypotonia is also presented followed by a basic diagnostic workup for the respective scenarios. This chapter further discusses how to differentiate central causes from peripheral causes of hypotonia in a newborn.


Newborn Hypotonia Floppy infant Central hypotonia Peripheral hypotonia Hypoxic-ischemic encephalopathy Prader-Willi syndrome Neuromuscular disorders 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of PediatricsNYU Winthrop HospitalMineolaUSA
  2. 2.SUNY Stony Brook School of MedicineStony BrookUSA

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