The Role of Radiation Therapy

  • Andre Tsin Chih ChenEmail author
  • Carlos Bo Chur Hong


The Intergroup 0116 (INT 0116) has established chemoradiation as the standard treatment for resected gastric cancer in Western countries. More recently, there has been a debate on the role of radiation in the treatment of diffuse-type adenocarcinoma of the stomach. Here we discuss the evidence and controversies that surround this issue. At this point of current knowledge, we recommend adjuvant chemoradiation for the treatment of resected diffuse-type adenocarcinoma of the stomach.


Gastric Cancer Diffuse Adjuvant Chemoradiation Radiotherapy 


5-FU + LV

5-fluorouracil plus leucovorin






Computerized tomography


Disease-free survival




Hazard ratio


Odds ratio


Overall survival


Relapse-free survival


Radiation therapy


Capecitabine and cisplatin


Capecitabine with radiation therapy


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Instituto do Câncer do Estado de São PauloSão PauloBrazil
  2. 2.Faculdade de Medicina da Universidade de São Paulo/Instituto do Câncer do Estado de São PauloSão PauloBrazil

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