Diffuse Unilateral Subacute Neuroretinitis (DUSN)

  • Stephen H. Tsang
  • Tarun SharmaEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1085)


  • Diffuse unilateral subacute neuroretinitis (DUSN) is caused by a subretinal live and mobile nematode.

  • Acute phase: Patients usually present with severe pain, decreased vision, vitritis/papillitis, and tracks of grayish-white lesions—and a live nematode.

  • Late phase: Arterial narrowing, optic atrophy, diffuse disruption of the retinal pigment epithelium (RPE), with severe visual loss


Phenocopies Diffuse unilateral subacute neuroretinitis DUSN 

Suggested Reading

  1. de Amorim Garcia Filho CA, Gomes AH, de A Garcia Soares AC, de Amorim Garcia CA. Clinical features of 121 patients with diffuse unilateral subacute neuroretinitis. Am J Ophthalmol. 2012;153:743–9.CrossRefGoogle Scholar
  2. Rosa AA, Rodrigues Neto Tdos S. Diffuse unilateral subacute neuroretinitis (DUSN): current update. Arq Bras Oftalmol. 2013;76:256–60. [Portuguese]CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative-Departments of Ophthalmology, Biomedical Engineering, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia UniversityNew YorkUSA
  2. 2.Department of Ophthalmology, Columbia UniversityEdward S. Harkness Eye Institute, NewYork-Presbyterian HospitalNew YorkUSA

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