Syphilis is an infectious disease caused by a spirochete, Treponema pallidum; it is most commonly spread by sexual transmission.
Syphilis is known as the “Great Imitator,” as systemic manifestations are variable. It can involve any part of the eye, with syphilitic uveitis being the most common type.
Congenital syphilis is characterized by Hutchinson’s teeth, saddle nose deformity, deafness, and interstitial keratitis; pigmentary changes in the retina are varied and patchy.
- Tsui E, Gal-Or O, Ghadiali Q, Freund KB. Multimodal imaging adds new insights into acute syphilitic posterior placoid chorioretinitis. Retin Cases Brief Rep. 2017; https://doi.org/10.1097/ICB.0000000000000645. [Epub ahead of print].