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Neuromuscular Diseases

  • Fabrizio Racca
  • Brunella Gily
Chapter

Abstract

Patients affected by neuromuscular disorders are at high risk of intraoperative and postoperative complications. General anesthesia in these patients may exacerbate respiratory and cardiovascular failure due to a marked sensitivity to several anesthetic drugs. Moreover, succinylcholine and halogenated agents can trigger life-threatening reactions. Thus, in these children, a proactive and multidisciplinary approach should be instituted before, during, and after any surgical procedure requiring general anesthesia or sedation. This chapter will review the pathophysiology of life-threatening complications of anesthesia in NMDs and the assessment and management of these patients before, during, and after anesthesia.

Keywords

Anesthesia Neuromuscular diseases Noninvasive ventilation Mechanical insufflation-exsufflation Malignant hyperthermia 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Fabrizio Racca
    • 1
  • Brunella Gily
    • 1
  1. 1.Department of Anesthesiology and Intensive CareSS Antonio Biagio e Cesare Arrigo HospitalAlessandriaItaly

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