Role of Microvascular Free Flaps Combined with Tissue Engineering

  • Waleed ZaidEmail author
  • Andrew Yampolsky
  • Beomjune Kim


The application of tissue engineering (TE) or regenerative medicine methods for reconstruction of maxillofacial continuity defects remains in its infancy. A number of authors have, however, reported successful use of TE for mandible reconstruction in humans and subhuman primates. TE products typically fall within the concept of the tissue engineering triad including constructs, stem cells, and signaling molecules. Although significant TE research is ongoing, only a few TE products are available to enhance mandibular continuity defect reconstruction, and none of them provide all aspects of the triad. In this section, we will share some areas where TE products can be beneficial as an adjunct to traditional reconstruction with vascularized grafts.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Oral and Maxillofacial SurgeryLouisiana Health Sciences Center in New OrleansNew OrleansUSA
  2. 2.Our Lady of the Lake Regional Medical CenterBaton RougeUSA

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