Meconium Ileus

  • Philip Corbett
  • Amulya SaxenaEmail author


Meconium ileus (MI) is neonatal intestinal obstruction caused by protein-rich, inspissated meconium in the terminal ileum. This viscid meconium adheres to the bowel wall, causing an intra-luminal obstruction (sometimes referred to as obturator-type obstruction). Its incidence is approximately 1:10,000 live births [1] within the white population but lower in other races. Historically, MI has been almost exclusively associated with cystic fibrosis (CF); however this dogma has been challenged by some published series that report 21–46% of their cases did not have CF [2, 3]. 10–20% of children born with CF present as MI [4, 5].


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Pediatric SurgeryChelsea Children’s Hospital, Chelsea and Westminster NHS Foundation Trust, Imperial College LondonLondonUK

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