Critical Care for Potential Liver Transplant Candidates: Ventilation
- 467 Downloads
End-stage liver disease or cirrhotic patients frequently require admission to an intensive care unit for the treatment of organ failure. Mechanical ventilation, which is frequently required, is consistently associated with a significantly increased rate of in-hospital mortality. Despite a lack of research focused on the cirrhotic population, there is a growing body of evidence from the general ICU or perioperative population showing that appropriate management of ventilatory support is associated with improved outcomes. Moreover, synergistic ventilatory strategies from the preoperative ICU period to the intraoperative and then the postoperative period may be an important pathway for further improvements in the outcomes of these patients.
KeywordsEnd-stage liver disease Cirrhosis Liver transplantation Mechanical ventilation
- 18.Fan E, et al. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 2017;195(9):1253–63.CrossRefGoogle Scholar
- 21.Blackwood B, et al. Protocolized versus non-protocolized weaning for reducing the duration of mechanical ventilation in critically ill adult patients. Cochrane Database Syst Rev. 2014;(11):CD006904.Google Scholar
- 26.Wang L, et al. Semi-recumbent position versus supine position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation. Cochrane Database Syst Rev. 2016;(1):CD009946.Google Scholar
- 31.Pedersen MR, et al. Pretransplant factors and associations with postoperative respiratory failure, ICU length of stay, and short-term survival after liver transplantation in a high MELD population. J Transp Secur. 2016;2016:6787854.Google Scholar