Secondary Malignant (Metastases)

  • Dominic H. Moon
  • Timothy M. Zagar


Brain metastasis is the most common indication for stereotactic radiosurgery (SRS). SRS is a safe and effective treatment modality for patients with good performance status and limited number of brain metastases. In addition, SRS serves as an adjuvant therapy for resected brain lesions. Accumulating studies also support the use of hypofractionated stereotactic radiotherapy (HSRT), or Fractionated stereotactic radiotherapy (FSRT) delivering 27–35 Gy in 3–5 fractions for relatively large brain lesions and resection beds.


Brain metastasis Stereotactic radiosurgery Hypofractionated stereotactic radiotherapy Whole-brain radiotherapy 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Dominic H. Moon
    • 1
  • Timothy M. Zagar
    • 2
  1. 1.Department of Radiation OncologyUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Northeastern Radiation OncologyPLLCSaratoga SpringsUSA

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