Cryotherapy for Barrett’s Esophagus

  • Nico Pagano
  • Raffaele Manta
  • Giuseppe Galloro


Cryotherapy has been applied in many fields of medicine to treat various diseases. In the last years this technique has been used to treat Barrett esophagus with different systems. Clinical results are at present to be considered slightly more than preliminary but they are promising. We don’t know which system performs better and the exact parameters of the treatment together with the correct technique have not yet been established. Strong evidence is lacking, particularly about long-term results. Notwithstanding this, current data seem to indicate a high efficacy of cryotherapy in the treatment of Barrett esophagus. The results of ongoing multicenter trial, and the data that will come from the future ones will help us find the correct position of cryotherapy in the treatment of Barrett esophagus.


Barrett esophagus Cryotherapy Cryoablation Endoscopy Treatment Esophageal cancer Therapeutic endoscopy 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Nico Pagano
    • 1
  • Raffaele Manta
    • 2
  • Giuseppe Galloro
    • 3
  1. 1.Gastroenterology and Digestive Endoscopy Unit, Department of Medical and Surgical Sciences (DIMEC)University Alma Mater Bologna, Italy—School of MedicineBolognaItaly
  2. 2.Gastroenterology and Digestive Endoscopy UnitNOCSAE Hospital of ModenaModenaItaly
  3. 3.Surgical Digestive Endoscopy Unit, Department of Clinical Medicine and SurgeryUniversity of Naples Federico II—School of MedicineNaplesItaly

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