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Nuclear Medicine in Neurological and Psychiatric Diagnosis

  • Majid Assadi
  • Hojjat Ahmadzadehfar
  • Hans-Jürgen Biersack
Chapter

Abstract

  1. 1.
    In blood–brain barrier imaging:
    1. (a)

      Longitudinal sinuses reveal a higher tracer uptake than the brain.

       
    2. (b)

      Transverse sinuses reveal a higher tracer uptake than the brain.

       
    3. (c)

      Blood–brain barrier imaging is performed by 99m-pertechnetate, 99mTc-DTPA, and 99mTc-glucoheptonate.

       
    4. (d)

      All of the above.

       
     
  2. 2.
    Which of the following is NOT a characteristic of the blood–brain barrier (BBB)?
    1. (a)

      High ionic permeability.

       
    2. (b)

      Existence of Na/K pump.

       
    3. (c)

      Low nonelectrolyte hydrophilic permeability.

       
    4. (d)

      It is a tight connection of endothelial cells.

       
     
  3. 3.
    Which of the following is a determinant of the transport of lipophilic agents from the blood–brain barrier (BBB)?
    1. (a)

      Na/K pump.

       
    2. (b)

      Calcium pump.

       
    3. (c)

      Glycoprotein pump.

       
    4. (d)

      The cerebral entry of lipophilic agents occurs without any intervention.

       
     
  4. 4.
    Which of the following factors is the least important in the permeability of the blood–brain barrier?
    1. (a)

      Lipophilicity.

       
    2. (b)

      Osmotic pressure.

       
    3. (c)

      Protein binding.

       
    4. (d)

      Hydrostatic pressure.

       
     
  5. 5.
    Which of the following patterns of BBB imaging in neonates with asphyxia indicates high brain involvement?
    1. (a)

      Typical stroke pattern of uptake in one of the large cerebral arteries.

       
    2. (b)

      Abnormal uptake in the intermediary region of large cerebral arteries.

       
    3. (c)

      Skull cap-like increase in uptake.

       
    4. (d)

      Abnormal focal uptake in the basal ganglia.

       
     

Suggested Readings

  1. 1.
    Ahmadzadehfar H, Biersack HJ, Freeman LM, Zuckier L. Clinical nuclear medicine. 2nd ed. Berlin: Springer; 2018.Google Scholar
  2. 2.
    Ell PJ, Gambhir SS. Nuclear medicine in clinical diagnosis and treatment. 3th ed. Edinburgh, NY: Churchill Livingstone; 2004.Google Scholar
  3. 3.
    Sandler MP, Coleman RE, Patton JA, Wackers FJT, Gottschalk A. Diagnostic nuclear medicine. 4th ed. Philadelphia: Lippincott & Williams Wilkins; 2003.Google Scholar
  4. 4.
    Henkin RE. Nuclear medicine. 2nd ed. Philadelphia: Mosby Elsevier; 2006.Google Scholar
  5. 5.
    Henriksen OM, Marner L, Law I. Clinical PET/MR imaging in dementia and neuro-oncology. PET Clin. 2016;11(4):441–52.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Majid Assadi
    • 1
  • Hojjat Ahmadzadehfar
    • 2
  • Hans-Jürgen Biersack
    • 3
  1. 1.Department of Nuclear MedicineBushehr University of Medical SciencesBushehrIran
  2. 2.Department of Nuclear MedicineUniversity Hospital BonnBonnGermany
  3. 3.Department of Nuclear MedicineUniverity Hospital BonnBonnGermany

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