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Fundamentals of Particle Interactions

  • Anthony J. Hickey
  • Stefano Giovagnoli
Chapter
Part of the AAPS Introductions in the Pharmaceutical Sciences book series (AAPSINSTR)

Abstract

The behavior of particles in bulk dictates their behavior. The forces of interaction between particles influence their flow and dispersion and the ease with which they can be suspended in any medium. These interactions are in the form of electrostatic and capillary forces that are reciprocally but not linearly related, mechanical interlocking arising from surface asperities and bulk van der Waals forces.

Pharmaceutical inhalation aerosols are a clear example of the way interparticulate forces influence particle behavior and illustrate the considerations that need to be given to these forces.

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Copyright information

© American Association of Pharmaceutical Scientists 2018

Authors and Affiliations

  • Anthony J. Hickey
    • 1
  • Stefano Giovagnoli
    • 2
  1. 1.Discovery Science and TechnologyRTI InternationalResearch Triangle ParkUSA
  2. 2.Department of Pharmaceutical SciencesUniversity of PerugiaPerugiaItaly

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