Comparison of T1 Mapping by Cardiac MRI to Non-cardiac MRI Methods to Evaluate Cardiac Fibrosis

  • Róisín B. Morgan
  • Michael Jerosch-Herold
  • Raymond Y. Kwong


The detection of possible underlying myocardial fibrosis is a common indication for cardiac MRI. In recent years the development of late gadolinium enhancement cardiac MRI (LGE-CMR) and T1 and T2 mapping techniques have revolutionized detection methods, previously predominantly performed by obtaining pathological specimens. Both focal fibrosis (scar) and diffuse fibrosis can be detected noninvasively by other cardiovascular imaging techniques, including nuclear cardiology techniques, echocardiography, and cardiac CT. In this chapter, these techniques are discussed in detail to explore how MRI compares to non-CMR methods of detecting cardiac fibrosis.


Fibrosis Cardiac magnetic resonance Gadolinium T1 mapping Hyperenhancement Myocardium MOLLI ShMOLLI Nuclear Positron emission Viability Perfusion Tissue Doppler imaging Backscatter Strain Speckle tracking Diastolic Computed tomography Multidetector 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Róisín B. Morgan
    • 1
  • Michael Jerosch-Herold
    • 2
  • Raymond Y. Kwong
    • 1
  1. 1.Non-invasive Cardiovascular Imaging, Cardiovascular Division, Department of MedicineBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA
  2. 2.Department of RadiologyBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA

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