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Just Another Autoantibody

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 21-year-old man is referred to the hospital’s emergency department (ED) by his primary care physician because of severe anemia (Hct 21%). The ED physician relates that the patient is a university student who has no significant past medical history and no history of transfusion. The patient was in his usual state of health until approximately 1 month ago when he experienced a flu-like illness following which he began to experience increasing fatigue and shortness of breath until he finally became quite lethargic and had difficulty to even get out of bed, prompting him to visit his doctor. A unit of RBCs is requested for transfusion. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank.

Keywords

Autoadsorption Least-incompatible Warm autoantibody Warm autoimmune hemolytic anemia 

References

  1. 1.
    Shizuma T. A patient with alcoholic liver cirrhosis who developed autoimmune hemolytic anemia following infection with influenza type A. JSM Biotechnol Bioeng. 2013;2(1):1019.Google Scholar
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    Bercovitz RS, Macy M, Ambruso DR. A case of autoimmune hemolytic anemia with anti-D specificity in a one-year-old. Immunohematology/American Red Cross. 2013;29(1):15–8.PubMedCentralGoogle Scholar

Recommended Reading

  1. Harmening DM, Rodberg K, Green REB. Autoimmune hemolytic anemias. In: Harmening DM, editor. Modern blood banking and transfusion practices. 6th ed. Philadelphia: F.A. Davis; 2012. p. 441–7.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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