Just Another Autoantibody
A 21-year-old man is referred to the hospital’s emergency department (ED) by his primary care physician because of severe anemia (Hct 21%). The ED physician relates that the patient is a university student who has no significant past medical history and no history of transfusion. The patient was in his usual state of health until approximately 1 month ago when he experienced a flu-like illness following which he began to experience increasing fatigue and shortness of breath until he finally became quite lethargic and had difficulty to even get out of bed, prompting him to visit his doctor. A unit of RBCs is requested for transfusion. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank.
KeywordsAutoadsorption Least-incompatible Warm autoantibody Warm autoimmune hemolytic anemia
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