A 33-year-old woman with a history of sickle cell disease is admitted with pain crisis (pain in extremities and back). The patient, who has no history of antibodies, has had several admissions to the hospital for pain crisis over the past 3 years and was transfused one unit of red blood cells (RBCs) 2 years ago; the RBCs were matched by extended phenotype (negative for C, E, and K antigens) as per your blood bank’s policy for sickle cell patients. The patient denies receiving any RBC transfusions since the one unit given 2 years ago at the hospital. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank.
Anti-K antibody Extended antigen matching Kell blood group Matuhasi–Ogata phenomenon Rh blood group Sickle cell
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