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The Platelet Transfusion

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 55-year-old man with a history of alcohol abuse and liver cirrhosis presents to the emergency department with upper gastrointestinal bleeding and symptomatic anemia related to acute blood loss (hemoglobin [Hgb] level 7.1 g/dL). A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) along with an order for two units of red blood cells (RBCs) is submitted to the blood bank.

Keywords

Apheresis platelets Isoantibody titers Platelet additive solution (PAS) Platelet transfusion Rh immune globulin Transfusion reaction 

Reference

  1. 1.
    Van der Meer PF. PAS or plasma for storage of platelets? A concise review. Transfus Med. 2016;26:339–42.CrossRefPubMedGoogle Scholar

Recommended Reading

  1. Cid J, Lozano M, Ziman A, West KA, et al. Low incidence of anti-D alloimmunization following D+ platelet transfusion. The anti-D alloimmunization after D-incompatible platelet transfusions (ADAPT) study. Br J Haematol. 2015;168(4):598–603.CrossRefPubMedGoogle Scholar
  2. Klein HG, Anstee DJ. Haemolytic transfusion reactions. In: Klein HG, Anstee DJ, editors. Mollison’s blood transfusion in clinical medicine. 12th ed. West Sussex: Wiley; 2014. p. 458–66.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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