Macroprolactinoma: Diagnosis and Management in a Patient with Infertility
A 31-year-old who had a history of delayed puberty and then developed amenorrhea after stopping birth control pills was found to have a macroprolactinoma. Cabergoline therapy resulted in normalization of prolactin and menstrual periods within 6 months. The adenoma size decreased slowly, and the patient conceived. The dopamine agonist was withdrawn upon conception and restarted postpartum. Visual fields were monitored during the pregnancy which was uneventful. The diagnosis and therapy of hyperprolactinemia in a patient seeking fertility and the peri-partum management of prolactinoma during pregnancy are discussed.
KeywordsProlactinoma Prolactin Infertility Amenorrhea Macroadenoma
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