Reflux in Pediatrics

  • Nina Gluchowski
  • Rachel Rosen


Gastroesophageal reflux (GER) is the passage of gastric contents into the esophagus with or without regurgitation or vomiting. This process occurs multiple times a day in healthy infants and children and most episodes cause few or no symptoms. When the refluxate reaches the mouth, the reflux is caused regurgitation. GER becomes gastroesophageal reflux disease (GERD) when the passage of gastric contents into the esophagus is associated with troublesome symptoms and/or complications. However, deciding what symptoms are troublesome is often difficult in children who are non-verbal or who are unable to accurately convey symptoms [1, 2].



Airway hyper-responsiveness


Anti regurgitation


Broncho-alveolar lavage


Chronic obstructive pulmonary disease


Gastroesophageal reflux


Gastroesophageal reflux disease




Laparoscopic anti-reflux surgery


Lower esophageal sphincter


Laryngo-pharyngeal reflux


Multiple intraluminal impedance


North American Society of Gastroenterology, Hepatology and Nutrition


Obstructive sleep apnea


Multiple intraluminal impedance with pH


Proton pump inhibitor


Sudden infant death syndrome


Transient lower esophageal sphincter relaxation


Transient lower esophageal sphincter relaxations


Vocal cord dysfunction


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Gastroenterology, Hepatology and Nutrition, Aerodigestive CenterBoston Children’s HospitalBostonUSA

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