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Acute REM Sleep Behavior Disorder

  • Federica ProviniEmail author
  • Naoko Tachibana
Chapter

Abstract

REM sleep behavior disorder (RBD) may occur acutely or subacutely, irrespective of age and sex. RBD or isolated REM sleep without atonia (RSWA) has been associated with various medications, or substance use/abuse, or abrupt withdrawal states. Less frequently, structural brain lesions (vascular, demyelinating disease, tumors), especially in the pontine region, may cause acute RBD. Also, RBD can appear acutely after a stressful life event and in post-traumatic stress disorder. RBD recognition in all these clinical conditions has a clinical value, but could have also a crucial importance in understanding the pathophysiology of RBD. More awareness of the existence of acute forms of RBD and greater familiarity with the various potential clinical pictures may help to avoid misdiagnoses and mistreatments. In addition, if prospective studies will confirm the existence of separate RBD patient subgroups (e.g., older men with neurodegenerative diseases, younger patients with narcolepsy, middle-aged women with depression taking antidepressants, and patients with autoimmune diseases), then prognostic differences and optimal treatments across RBD subgroups could emerge.

Keywords

Antidepressants Selective serotonin reuptake inhibitors (SSRI) Substance abuse Alcohol withdrawal Ischemic lesions Autoimmune diseases Paraneoplastic diseases Morvan’s syndrome Fatal familial insomnia Oneiric stupor Post-traumatic stress disorder (PTSD) 

Notes

Acknowledgments

We are grateful to Luca Baldelli for literature searching and revision, Cecilia Baroncini for English editing, and Elena Zoni for graphic production.

References

  1. 1.
    Schenck CH, Bundlie SR, Ettinger MG, Mahowald MW. Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep. 1986;9(2):293–308.CrossRefGoogle Scholar
  2. 2.
    Iranzo A, Aparicio J. A lesson from anatomy: focal brain lesions causing REM sleep behavior disorder. Sleep Med. 2009;10(1):9–12.  https://doi.org/10.1016/j.sleep.2008.03.005.CrossRefPubMedGoogle Scholar
  3. 3.
    Winkelman JW, James L. Serotonergic antidepressants are associated with REM sleep without atonia. Sleep. 2004;27(2):317–21.CrossRefGoogle Scholar
  4. 4.
    Hoque R, Chesson AL Jr. Pharmacologically induced/exacerbated restless legs syndrome, periodic limb movements of sleep, and REM behavior disorder/REM sleep without atonia: literature review, qualitative scoring, and comparative analysis. J Clin Sleep Med. 2010;6(1):79–83.PubMedPubMedCentralGoogle Scholar
  5. 5.
    Mahowald MW, Schenck CH. REM sleep parasomnias. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. Philadelphia: Elsevier Saunders; 2010. p. 1083–97.Google Scholar
  6. 6.
    Postuma RB, Gagnon JF, Tuineaig M, Bertrand JA, Latreille V, Desjardins C, et al. Antidepressants and REM sleep behavior disorder: isolated side effect or neurodegenerative signal? Sleep. 2013;36(11):1579–85.  https://doi.org/10.5665/sleep.3102.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Lee K, Baron K, Soca R, Attarian H. The prevalence and characteristics of REM sleep without atonia (RSWA) in patients taking antidepressants. J Clin Sleep Med. 2016;12(3):351–5.  https://doi.org/10.5664/jcsm.5582.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Reynolds CF 3rd, Kupfer DJ. Sleep research in affective illness: state of the art circa 1987. Sleep. 1987;10(3):199–215.CrossRefGoogle Scholar
  9. 9.
    Schenck CH, Mahowald MW, Kim SW, O’Connor KA, Hurwitz TD. Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder. Sleep. 1992;15(3):226–35.CrossRefGoogle Scholar
  10. 10.
    Niiyama Y, Shimizu T, Abe M, Hishikawa Y. Cortical reactivity in REM sleep with tonic mentalis EMG activity induced by clomipramine: an evaluation by slow vertex response. Electroencephalogr Clin Neurophysiol. 1993;86(4):247–51.CrossRefGoogle Scholar
  11. 11.
    Zhang B, Hao Y, Jia F, Tang Y, Li X, Liu W, et al. Sertraline and rapid eye movement sleep without atonia: an 8-week, open-label study of depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 2013;47:85–92.  https://doi.org/10.1016/j.pnpbp.2013.08.010.CrossRefGoogle Scholar
  12. 12.
    Sheyner I, Khan S, Stewart JT. A case of selective serotonin reuptake inhibitor-induced rapid eye movement behavior disorder. J Am Geriatr Soc. 2010;58(7):1421–2.CrossRefGoogle Scholar
  13. 13.
    Bental E, Lavie P, Sharf B. Severe hypermotility during sleep in treatment of cataplexy with clomipramine. Isr J Med Sci. 1979;15(7):607–9.Google Scholar
  14. 14.
    Matsumoto M, Mutoh F, Naoe H, Kamata S, Chiba S, Miyagishi T. The effects of imipramine on REM sleep behavior disorder in 3 cases. Sleep Res. 1991;20A:351.Google Scholar
  15. 15.
    Attarian HP, Schenck CH, Mahowald MW. Presumed REM sleep behavior disorder arising from cataplexy and wakeful dreaming. Sleep Med. 2000;1(2):131–3.CrossRefGoogle Scholar
  16. 16.
    Parish JM. Violent dreaming and antidepressant drugs: or how paroxetine made me dream that I was fighting Saddam Hussein. J Clin Sleep Med. 2007;3(5):529–31.PubMedPubMedCentralGoogle Scholar
  17. 17.
    Guilleminault C, Raynal D, Takahashi S, Carskadon M, Dement W. Evaluation of short-term and long-term treatment of the narcolepsy syndrome with clomipramine hydrochloride. Acta Neurol Scand. 1976;54(1):71–87.CrossRefGoogle Scholar
  18. 18.
    Olson EJ, Boeve BF, Silber MH. Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain. 2000;123(Pt 2):331–9.CrossRefGoogle Scholar
  19. 19.
    Schutte S, Doghramji K. REM behavior disorder seen with venlafaxine (Effexor). Sleep Res. 1996;25:364.Google Scholar
  20. 20.
    Iranzo A, Graus F, Clover L, Morera J, Bruna J, Vilar C, et al. Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. Ann Neurol. 2006;59(1):178–81.  https://doi.org/10.1002/ana.20693.CrossRefGoogle Scholar
  21. 21.
    Onofrj M, Luciano AL, Thomas A, Iacono D, D’Andreamatteo G. Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. Neurology. 2003;60(1):113–5.CrossRefGoogle Scholar
  22. 22.
    Teman PT, Tippmann-Peikert M, Silber MH, Slocumb NL, Auger RR. Idiopathic rapid-eye-movement sleep disorder: associations with antidepressants, psychiatric diagnoses, and other factors, in relation to age of onset. Sleep Med. 2009;10(1):60–5.  https://doi.org/10.1016/j.sleep.2007.11.019.CrossRefGoogle Scholar
  23. 23.
    Ju YE. Rapid eye movement sleep behavior disorder in adults younger than 50 years of age. Sleep Med. 2013;14(8):768–74.  https://doi.org/10.1016/j.sleep.2012.09.026.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Lam SP, Fong SY, Ho CK, Yu MW, Wing YK. Parasomnia among psychiatric outpatients: a clinical, epidemiologic, cross-sectional study. J Clin Psychiatry. 2008;69(9):1374–82.CrossRefGoogle Scholar
  25. 25.
    Lam SP, Zhang J, Tsoh J, Li SX, Ho CK, Mok V, et al. REM sleep behavior disorder in psychiatric populations. J Clin Psychiatry. 2010;71(8):1101–3.  https://doi.org/10.4088/JCP.l05877gry.CrossRefGoogle Scholar
  26. 26.
    Lam SP, Li SX, Mok V, Wing YK. Young-onset REM sleep behavior disorder: beyond the antidepressant effect. Sleep Med. 2012;13(2):211.  https://doi.org/10.1016/j.sleep.2011.04.018.CrossRefPubMedGoogle Scholar
  27. 27.
    Lam SP, Li SX, Chan JW, Mok V, Tsoh J, Chan A, et al. Does rapid eye movement sleep behavior disorder exist in psychiatric populations? A clinical and polysomnographic case-control study. Sleep Med. 2013;14(8):788–94.  https://doi.org/10.1016/j.sleep.2012.05.016.CrossRefGoogle Scholar
  28. 28.
    Takahashi T, Mitsuya H, Murata T, Murayama J, Wada Y. Opposite effects of SSRIs and tandospirone in the treatment of REM sleep behavior disorder. Sleep Med. 2008;9(3):317–9.  https://doi.org/10.1016/j.sleep.2007.05.003.CrossRefPubMedGoogle Scholar
  29. 29.
    Schenck CH, Hurwitz TD, Mahowald MW. REM sleep behavior disorder. Am J Psychiatry. 1988;145(5):652.PubMedGoogle Scholar
  30. 30.
    Louden MB, Morehead MA, Schmidt HS. Activation by selegiline (Eldepryle) of REM sleep behavior disorder in parkinsonism. W V Med J. 1995;91(3):101.PubMedGoogle Scholar
  31. 31.
    Akindele MO, Evans JI, Oswald I. Mono-amine oxidase inhibitors, sleep and mood. Electroencephalogr Clin Neurophysiol. 1970;29(1):47–56.CrossRefGoogle Scholar
  32. 32.
    Mike ME, Kranz AJ. MAOI suppression of RBD refractory to clonazepam and other agents. Sleep Res. 1996;25:63.Google Scholar
  33. 33.
    Carlander B, Touchon J, Ondze B, Billiard M. REM sleep behavior disorder induced by cholinergic treatment in Alzheimer’s disease. J Sleep Res. 1996;5(Suppl 1):28.Google Scholar
  34. 34.
    Yeh SB, Yeh PY, Schenck CH. Rivastigmine-induced REM sleep behavior disorder (RBD) in a 88-year-old man with Alzheimer’s disease. J Clin Sleep Med. 2010;6(2):192–5.PubMedPubMedCentralGoogle Scholar
  35. 35.
    Ringman JM, Simmons JH. Treatment of REM sleep behavior disorder with donepezil: a report of three cases. Neurology. 2000;55(6):870–1.CrossRefGoogle Scholar
  36. 36.
    Tan L, Zhou J, Liang B, Li Y, Lei F, Du L, et al. A case of quetiapine-induced rapid eye movement sleep behavior disorder. Biol Psychiatry. 2016;79(5):e11–2.  https://doi.org/10.1016/j.biopsych.2014.08.002.CrossRefPubMedGoogle Scholar
  37. 37.
    Iranzo A, Santamaria J. Bisoprolol-induced rapid eye movement sleep behavior disorder. Am J Med. 1999;107(4):390–2.CrossRefGoogle Scholar
  38. 38.
    Morrison I, Frangulyan R, Riha RL. Beta-blockers as a cause of violent rapid eye movement sleep behavior disorder: a poorly recognized but common cause of violent parasomnias. Am J Med. 2011;124(1):e11.  https://doi.org/10.1016/j.amjmed.2010.04.023.CrossRefGoogle Scholar
  39. 39.
    Ohayon MM, Caulet M, Priest RG. Violent behavior during sleep. J Clin Psychiatry. 1997;58(8):369–76; quiz 77.CrossRefGoogle Scholar
  40. 40.
    Stolz S, Aldrich M. REM sleep behavior disorder associated with caffeine abuse. Sleep Res. 1991;20:341.Google Scholar
  41. 41.
    Vorona RD, Ware JC. Exacerbation of REM sleep behavior disorder by chocolate ingestion: a case report. Sleep Med. 2002;3(4):365–7.CrossRefGoogle Scholar
  42. 42.
    Silber MH. REM sleep behavior disorder associated with barbiturate withdrawal. Sleep Res. 1996;25:371.Google Scholar
  43. 43.
    Tachibana M, Tanaka K, Hishikawa Y, Kaneko Z. A sleep study of acute psychotic states due to alcohol and meprobamate addiction. Adv Sleep Res. 1975;2:177–205.Google Scholar
  44. 44.
    Tanaka K, Kameda H, Sugita Y, Hishikawa Y. [A case with pentazocine dependence developing delirium on withdrawal (author’s transl)]. Seishin Shinkeigaku Zasshi. 1979;81(4):289–99.Google Scholar
  45. 45.
    Sugano T, Suenaga K, Endo S. [Withdrawal delirium in a patient with nitrazepam addiction (in Japanese)]. Jpn J EEG EMG. 1980;8:34–5.Google Scholar
  46. 46.
    Fisher C. Physiological concomitants of unconscious mental processes: some clinical and therapeutic application of recent research on sleep and dreaming. In: Prangshvili AS, Sherozia AE, Bassin FV, editors. The unconscious: nature, functions, methods of study. Tblisi, USSR: Metsniereba Publishing House; 1978. p. 81–5.Google Scholar
  47. 47.
    Gross MM, Goodenough D, Tobin M, Halpert E, Lepore D, Perlstein A, et al. Sleep disturbances and hallucinations in the acute alcoholic psychoses. J Nerv Ment Dis. 1966;142(6):493–514.CrossRefGoogle Scholar
  48. 48.
    Kotorii T, Nakazawa Y, Yokoyama T, Kurauchi H, Sakurada H, Ohkawa T, et al. The sleep pattern of chronic alcoholics during the alcohol withdrawal period. Folia Psychiatr Neurol Jpn. 1980;34(2):89–95.PubMedGoogle Scholar
  49. 49.
    Hishikawa Y, Sugita Y, Teshima Y, Iijima S, Tanaka K, Tachibana M. Sleep disorders in alcoholic patients with delirium tremens and transient withdrawal hallucinations, reevaluation of the REM rebound and intrusion theory. In: Karacan I, editor. Psychophysiological aspects of sleep: proceedings of the third International Congress of Sleep Research. Park Ridge: Noyes Medical Publishers; 1981. p. 109–22.Google Scholar
  50. 50.
    Plazzi G, Montagna P, Meletti S, Lugaresi E. Polysomnographic study of sleeplessness and oneiricisms in the alcohol withdrawal syndrome. Sleep Med. 2002;3(3):279–82.CrossRefGoogle Scholar
  51. 51.
    Lugaresi E, Medori R, Montagna P, Baruzzi A, Cortelli P, Lugaresi A, et al. Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei. N Engl J Med. 1986;315(16):997–1003.  https://doi.org/10.1056/NEJM198610163151605.CrossRefPubMedGoogle Scholar
  52. 52.
    Provini F, Cortelli P, Montagna P, Gambetti P, Lugaresi E. Fatal insomnia and agrypnia excitata: sleep and the limbic system. Rev Neurol (Paris). 2008;164(8–9):692–700.  https://doi.org/10.1016/j.neurol.2007.11.003.CrossRefGoogle Scholar
  53. 53.
    Guaraldi P, Calandra-Buonaura G, Terlizzi R, Montagna P, Lugaresi E, Tinuper P, et al. Oneiric stupor: the peculiar behaviour of agrypnia excitata. Sleep Med. 2011;12(Suppl 2):S64–7.  https://doi.org/10.1016/j.sleep.2011.10.014.CrossRefGoogle Scholar
  54. 54.
    Montagna P, Lugaresi E. Agrypnia Excitata: a generalized overactivity syndrome and a useful concept in the neurophysiopathology of sleep. Clin Neurophysiol. 2002;113(4):552–60.CrossRefGoogle Scholar
  55. 55.
    Lugaresi E, Provini F, Montagna P. The neuroanatomy of sleep. Considerations on the role of the thalamus in sleep and a proposal for a caudorostral organization. Eur J Anat. 2004;8:85–93.Google Scholar
  56. 56.
    Culebras A, Moore JT. Magnetic resonance findings in REM sleep behavior disorder. Neurology. 1989;39(11):1519–23.CrossRefGoogle Scholar
  57. 57.
    Schenck CH, Mahowald MW. A polysomnographic, neurologic, psychiatric, and clinical outcome report on 70 consecutive cases with REM sleep behavior disorder (RBD): sustained clonazepam efficacy in 89.5% of 57 treated patients. Clev Clin J Med. 1990;57:S9–S23.CrossRefGoogle Scholar
  58. 58.
    Kimura K, Tachibana N, Kohyama J, Otsuka Y, Fukazawa S, Waki R. A discrete pontine ischemic lesion could cause REM sleep behavior disorder. Neurology. 2000;55(6):894–5.CrossRefGoogle Scholar
  59. 59.
    Peter A, Hansen ML, Merkl A, Voigtlander S, Bajbouj M, Danker-Hopfe H. REM sleep behavior disorder and excessive startle reaction to visual stimuli in a patient with pontine lesions. Sleep Med. 2008;9(6):697–700.  https://doi.org/10.1016/j.sleep.2007.10.009.CrossRefPubMedGoogle Scholar
  60. 60.
    Xi Z, Luning W. REM sleep behavior disorder in a patient with pontine stroke. Sleep Med. 2009;10(1):143–6.  https://doi.org/10.1016/j.sleep.2007.12.002.CrossRefPubMedGoogle Scholar
  61. 61.
    Reynolds TQ, Roy A. Isolated cataplexy and REM sleep behavior disorder after pontine stroke. J Clin Sleep Med. 2011;7(2):211–3.PubMedPubMedCentralGoogle Scholar
  62. 62.
    Felix S, Thobois S, Peter-Derex L. Rapid eye movement sleep behaviour disorder symptomatic of a brain stem cavernoma. J Sleep Res. 2016;25(2):211–5.  https://doi.org/10.1111/jsr.12364.CrossRefPubMedGoogle Scholar
  63. 63.
    Zambelis T, Paparrigopoulos T, Soldatos CR. REM sleep behaviour disorder associated with a neurinoma of the left pontocerebellar angle. J Neurol Neurosurg Psychiatry. 2002;72(6):821–2.CrossRefGoogle Scholar
  64. 64.
    Schenck CH, Mahowald MW. REM sleep behavior disorder: clinical, developmental, and neuroscience perspectives 16 years after its formal identification in SLEEP. Sleep. 2002;25(2):120–38.CrossRefGoogle Scholar
  65. 65.
    Jianhua C, Xiuqin L, Quancai C, Heyang S, Yan H. Rapid eye movement sleep behavior disorder in a patient with brainstem lymphoma. Intern Med. 2013;52(5):617–21.  https://doi.org/10.2169/internalmedicine.52.8786.CrossRefGoogle Scholar
  66. 66.
    Plazzi G, Montagna P. Remitting REM sleep behavior disorder as the initial sign of multiple sclerosis. Sleep Med. 2002;3(5):437–9.CrossRefGoogle Scholar
  67. 67.
    Tippmann-Peikert M, Boeve BF, Keegan BM. REM sleep behavior disorder initiated by acute brainstem multiple sclerosis. Neurology. 2006;66(8):1277–9.  https://doi.org/10.1212/01.wnl.0000208518.72660.ff.CrossRefGoogle Scholar
  68. 68.
    Gomez-Choco MJ, Iranzo A, Blanco Y, Graus F, Santamaria J, Saiz A. Prevalence of restless legs syndrome and REM sleep behavior disorder in multiple sclerosis. Mult Scler. 2007;13(6):805–8.  https://doi.org/10.1177/1352458506074644.CrossRefPubMedPubMedCentralGoogle Scholar
  69. 69.
    Mathis J, Hess CW, Bassetti C. Isolated mediotegmental lesion causing narcolepsy and rapid eye movement sleep behaviour disorder: a case evidencing a common pathway in narcolepsy and rapid eye movement sleep behaviour disorder. J Neurol Neurosurg Psychiatry. 2007;78(4):427–9.  https://doi.org/10.1136/jnnp.2006.099515.CrossRefPubMedPubMedCentralGoogle Scholar
  70. 70.
    Lin FC, Liu CK, Hsu CY. Rapid-eye-movement sleep behavior disorder secondary to acute aseptic limbic encephalitis. J Neurol. 2009;256(7):1174–6.  https://doi.org/10.1007/s00415-009-5067-9.CrossRefPubMedPubMedCentralGoogle Scholar
  71. 71.
    St Louis EK, McCarter SJ, Boeve BF, Silber MH, Kantarci K, Benarroch EE, et al. Lesional REM sleep behavior disorder localizes to the dorsomedial pons. Neurology. 2014;83(20):1871–3.  https://doi.org/10.1212/WNL.0000000000000978.CrossRefPubMedPubMedCentralGoogle Scholar
  72. 72.
    De Barros-Ferreira M, Chodkiewicz JP, Lairy GC, Salzarulo P. Disorganized relations of tonic and phasic events of REM sleep in a case of brain-stem tumour. Electroencephalogr Clin Neurophysiol. 1975;38(2):203–7.CrossRefGoogle Scholar
  73. 73.
    Provini F, Vetrugno R, Pastorelli F, Lombardi C, Plazzi G, Marliani AF, et al. Status dissociatus after surgery for tegmental ponto-mesencephalic cavernoma: a state-dependent disorder of motor control during sleep. Mov Disord. 2004;19(6):719–23.  https://doi.org/10.1002/mds.20027.CrossRefGoogle Scholar
  74. 74.
    Condurso R, Aricò I, Romanello G, Cervasi G, Silvestri R. Status dissociatus in multilacunar encephalopathy with median pontine lesion: a video-polygraphic presentation in “Parasomnias—Other Sleep Disorders”. J Sleep Res. 2006;15:211–5.  https://doi.org/10.1111/j.1365-2869.2006.00540_52.x.CrossRefGoogle Scholar
  75. 75.
    Schenck CH, Boyd JL, Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep. 1997;20(11):972–81.CrossRefGoogle Scholar
  76. 76.
    Limousin N, Dehais C, Gout O, Heran F, Oudiette D, Arnulf I. A brainstem inflammatory lesion causing REM sleep behavior disorder and sleepwalking (parasomnia overlap disorder). Sleep Med. 2009;10(9):1059–62.  https://doi.org/10.1016/j.sleep.2008.12.006.CrossRefGoogle Scholar
  77. 77.
    Piette T, Mescola P, Uytdenhoef P, Henriet M, Vanderkelen B, Jacquy J, et al. A unique episode of REM sleep behavior disorder triggered during surgery for Parkinson’s disease. J Neurol Sci. 2007;253(1–2):73–6.  https://doi.org/10.1016/j.jns.2006.11.005.CrossRefPubMedGoogle Scholar
  78. 78.
    Vale TC, Fernandes do Prado LB, do Prado GF, Povoas Barsottini OG, Pedroso JL. Rapid eye movement sleep behavior disorder in paraneoplastic cerebellar degeneration: improvement with immunotherapy. Sleep. 2016;39(1):117–20.  https://doi.org/10.5665/sleep.5330.CrossRefPubMedPubMedCentralGoogle Scholar
  79. 79.
    Shinno H, Kamei M, Maegawa T, Satake A, Inami Y, Horiguchi J, et al. Three patients with cancer who developed rapid-eye-movement sleep behavior disorder. J Pain Symptom Manage. 2010;40(3):449–52.  https://doi.org/10.1016/j.jpainsymman.2010.01.016.CrossRefPubMedGoogle Scholar
  80. 80.
    Compta Y, Iranzo A, Santamaria J, Casamitjana R, Graus F. REM sleep behavior disorder and narcoleptic features in anti-Ma2-associated encephalitis. Sleep. 2007;30(6):767–9.CrossRefGoogle Scholar
  81. 81.
    Adams C, McKeon A, Silber MH, Kumar R. Narcolepsy, REM sleep behavior disorder, and supranuclear gaze palsy associated with Ma1 and Ma2 antibodies and tonsillar carcinoma. Arch Neurol. 2011;68(4):521–4.  https://doi.org/10.1001/archneurol.2011.56.CrossRefGoogle Scholar
  82. 82.
    Liguori R, Vincent A, Clover L, Avoni P, Plazzi G, Cortelli P, et al. Morvan’s syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels. Brain. 2001;124(Pt 12):2417–26.CrossRefGoogle Scholar
  83. 83.
    Cochen V, Arnulf I, Demeret S, Neulat ML, Gourlet V, Drouot X, et al. Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barre syndrome. Brain. 2005;128(Pt 11):2535–45.  https://doi.org/10.1093/brain/awh585.CrossRefGoogle Scholar
  84. 84.
    Fernandez-Arcos A, Iranzo A, Serradell M, Gaig C, Santamaria J. The clinical phenotype of idiopathic rapid eye movement sleep behavior disorder at presentation: a study in 203 consecutive patients. Sleep. 2016;39(1):121–32.  https://doi.org/10.5665/sleep.5332.CrossRefPubMedPubMedCentralGoogle Scholar
  85. 85.
    Schenck CH. Expanded insights into idiopathic REM sleep behavior disorder. Sleep. 2016;39(1):7–9.  https://doi.org/10.5665/sleep.5300.CrossRefPubMedPubMedCentralGoogle Scholar
  86. 86.
    American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC; 2013.Google Scholar
  87. 87.
    Ross RJ, Ball WA, Dinges DF, Kribbs NB, Morrison AR, Silver SM, et al. Motor dysfunction during sleep in posttraumatic stress disorder. Sleep. 1994;17(8):723–32.CrossRefGoogle Scholar
  88. 88.
    Hefez A, Metz L, Lavie P. Long-term effects of extreme situational stress on sleep and dreaming. Am J Psychiatry. 1987;144(3):344–7.  https://doi.org/10.1176/ajp.144.3.344.CrossRefGoogle Scholar
  89. 89.
    Husain AM, Miller PP, Carwile ST. REM sleep behavior disorder: potential relationship to post-traumatic stress disorder. J Clin Neurophysiol. 2001;18(2):148–57.CrossRefGoogle Scholar
  90. 90.
    Wallace DM, Shafazand S, Ramos AR, Carvalho DZ, Gardener H, Lorenzo D, et al. Insomnia characteristics and clinical correlates in Operation Enduring Freedom/Operation Iraqi Freedom veterans with post-traumatic stress disorder and mild traumatic brain injury: an exploratory study. Sleep Med. 2011;12(9):850–9.  https://doi.org/10.1016/j.sleep.2011.06.004.CrossRefPubMedGoogle Scholar
  91. 91.
    Mysliwiec V, O’Reilly B, Polchinski J, Kwon HP, Germain A, Roth BJ. Trauma associated sleep disorder: a proposed parasomnia encompassing disruptive nocturnal behaviors, nightmares, and REM without atonia in trauma survivors. J Clin Sleep Med. 2014;10(10):1143–8.  https://doi.org/10.5664/jcsm.4120.CrossRefPubMedPubMedCentralGoogle Scholar
  92. 92.
    Mysliwiec V, Brock MS, Creamer JL, O’Reilly BM, Germain A, Roth BJ. Trauma associated sleep disorder: a parasomnia induced by trauma. Sleep Med Rev. 2018;37:94–104.  https://doi.org/10.1016/j.smrv.2017.01.004.CrossRefPubMedGoogle Scholar
  93. 93.
    Manni R, Ratti PL, Terzaghi M. Secondary “incidental” REM sleep behavior disorder: do we ever think of it? Sleep Med. 2011;12(Suppl 2):S50–3.  https://doi.org/10.1016/j.sleep.2011.10.011.CrossRefPubMedGoogle Scholar
  94. 94.
    Jennum P, Mayer G, Ju YE, Postuma R. Morbidities in rapid eye movement sleep behavior disorder. Sleep Med. 2013;14(8):782–7.  https://doi.org/10.1016/j.sleep.2012.11.002.CrossRefPubMedPubMedCentralGoogle Scholar
  95. 95.
    Frauscher B, Gschliesser V, Brandauer E, Marti I, Furtner MT, Ulmer H, et al. REM sleep behavior disorder in 703 sleep-disorder patients: the importance of eliciting a comprehensive sleep history. Sleep Med. 2010;11(2):167–71.  https://doi.org/10.1016/j.sleep.2009.03.011.CrossRefPubMedPubMedCentralGoogle Scholar

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Authors and Affiliations

  1. 1.IRCCS, Institute of Neurological Sciences of Bologna, Bellaria HospitalBolognaItaly
  2. 2.Department of Biomedical and Neuromotor SciencesUniversity of BolognaBolognaItaly
  3. 3.Center for Sleep-related Disorders, Kansai Electric Power HospitalOsakaJapan
  4. 4.Division of Sleep MedicineKansai Electric Power Medical Research InstituteOsakaJapan

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