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PET Hybrid Imaging of the Thorax

  • Deena Neriman
  • Ali Vahedi
  • Stefan Voo
  • James Connelly
  • Francesco Fraioli
Chapter

Abstract

For many years scintigraphy, planar imaging of radioactive emission using a large area detector, formed the backbone of nuclear medicine techniques with low spatial resolution but high sensitivity. Combined with the properties of a tracer, a substance labelled with a radioactive element (radionuclide), the technique could be used for imaging tissue properties or physiological processes. Advances in engineering and computing technology allowed the technique to move into 3-dimensional image reconstruction and then combined with radiological techniques, particularly CT, to provide state-of-the-art hybrid imaging techniques. Positron-emission tomography (PET) is fast becoming the dominant nuclear medicine technique, due to its higher sensitivity and resolution than single-photon-emission computed tomography (SPECT). It has been widely used for investigating malignant diseases and increasingly used for inflammatory diseases and infection. Whilst computed tomography (CT) images represent a snapshot of patient anatomy, radiopharmaceuticals and PET provide the means to image pathophysiology.

Keywords

PET SUV PET tracers PET lymphoma PET mesothelioma PET oesophagus PET lung PET thymoma PET infection PET PUO PET immunodeficiency PET Vasculitis PET Sarcoidosis PET ILD PET autoimmune Nuclear MPS Nuclear MPI Nuclear chest PET cardiac PET chest 

Notes

Acknowledgments

Thanks to Dr. Leon Menezes for the cardiac sarcoid case, and to Dr. Ben Thomas and Dr. Trine Hjørnevik for commenting on the physics and technical part of the manuscript.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Deena Neriman
    • 1
  • Ali Vahedi
    • 1
  • Stefan Voo
    • 1
  • James Connelly
    • 1
  • Francesco Fraioli
    • 1
  1. 1.University College London HospitalsLondonUK

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