Oesophagus: Inflammatory Patterns

  • Mahsa S. Ahadi
  • Anthony J. Gill
  • John R. Turchini
  • Spiro C. Raftopoulos
  • M. Priyanthi Kumarasinghe


Identifying inflammatory patterns in an oesophageal biopsy often gives important clues that lead to a specific aetiological diagnosis. Another important aspect of dealing with nonneoplastic oesophageal biopsies is to correctly identify conditions that have a potential to neoplastic progression as they need closer surveillance. It is vital to correlate the microscopic pattern in an endoscopic biopsy with clinical and endoscopic clues. This chapter details the patterns, clues and pitfalls in biopsy interpretation that leads to a clinically relevant conclusion highlighting key points. In addition to providing strategies for dealing with reactionary patterns, a series of short clinical stories that correlate important clinical, endoscopic and pathologic features are included. Illustration of key points and features are facilitated by a large number of high-quality photomicrographs.


Inflammatory patterns Oesophageal biopsy Nonneoplastic oesophageal lesions Neoplastic oesophageal lesions 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Mahsa S. Ahadi
    • 1
  • Anthony J. Gill
    • 2
  • John R. Turchini
    • 3
  • Spiro C. Raftopoulos
    • 4
    • 5
  • M. Priyanthi Kumarasinghe
    • 6
  1. 1.Department of Anatomical PathologyRoyal North Shore Hospital, University of SydneySt. LeonardsAustralia
  2. 2.Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore HospitalUniversity of SydneySt. LeonardsAustralia
  3. 3.Department of Anatomical Pathology, Royal North Shore HospitalThe University of SydneySt LeonardsAustralia
  4. 4.Interventional Endoscopist and Gastroenterologist, Department of GastroenterologySir Charles Gairdner HospitalNedlandsAustralia
  5. 5.University of Western AustraliaPerthAustralia
  6. 6.Department of Anatomical Pathology, PathWest Laboratory MedicineQEII Medical Centre and University of Western AustraliaPerthAustralia

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