The Esophagogastric Junction

  • Qin Huang


Accurate identification of the esophagogastric junction (EGJ) is crucial for EGJ disease diagnosis, classification, and treatment in daily practice. Although a universally accepted criterion for EGJ has not been established, the most commonly used landmark for endoscopic mucosal EGJ is the proximal end of gastric longitudinal mucosal folds with a high reproducibility in different populations. As to histologic EGJ markers, the distal ends of deep esophageal glands and ducts, squamous epithelium, and multilayered epithelium are well recognized as reliable landmarks because those structures occur only in the esophagus.


Esophagogastric junction Stomach Esophagus Multilayered epithelium Esophageal gland 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Qin Huang
    • 1
    • 2
  1. 1.Pathology and Laboratory MedicineVeterans Affairs Boston Healthcare SystemWest RoxburyUSA
  2. 2.Harvard Medical School and Brigham and Women’s HospitalBostonUSA

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