Management of Recurrent Lymph Nodes in Central and Lateral Neck in the Follow-Up of Differentiated Thyroid Carcinoma

  • Seyfettin Ilgan


Despite excellent overall prognosis, up to 40% of patients with papillary thyroid cancer (PTC) will have persistent or recurrent disease, mostly in lateral (53%) or central (28%) cervical lymph nodes. Local and regional recurrences continue to be treated by surgical excision with or without adjuvant radioiodine treatment, especially in potentially curable patients. Discovery of nonpalpable nodal recurrences in the central and lateral neck have been increased considerably with the evolving role of ultrasonography in the follow-up of patients with PTC. However, the management of impalpable or indolent locoregional recurrences of PTC continues to be more controversial. Despite arguments over survival benefit of reoperations, 19–73% remission rates have been reported based on Tg levels with compartment-oriented reoperations. The correct delineation of the disease preoperatively and the use of new techniques facilitating identification of recurrent laryngeal nerve and metastatic foci during surgery are essential parts of therapeutic success.


Thyroid cancer Lymph node Metastases Radioguided surgery 


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© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Seyfettin Ilgan
    • 1
  1. 1.Department of Nuclear MedicineGüven HospitalAnkaraTurkey

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