Polymyalgia rheumatica (PMR) is an inflammatory disease commonly affecting adults over the age of 50 years and presents with symmetric proximal stiffness and aches in the shoulders, neck, and/or pelvic girdle. An elevated erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) are commonly seen. Treatment includes low-dose corticosteroids tapered slowly over weeks to months. Giant cell arteritis, a systemic vasculitis that can affect the aorta and its branches, can present concurrently or may develop during the course of PMR. Close monitoring for GCA is required in all PMR patients and treatment with higher doses of corticosteroids promptly initiated when suspected.