Seronegative Spondyloarthropathies

  • Eren O. Kuris


Rheumatologic disorders can contribute substantially to inflammatory arthropathies of the axial and appendicular skeleton. Seronegative spondyloarthropathies refer to various systemic rheumatologic disorders that are traditionally negative for rheumatoid factor (RF). Many of these conditions can be treated early and effectively with biologic agents prior to the manifestation of skeletal damage.


Seronegative spondyloarthropathies Ankylosing spondylitis HLA-B27 DMARDs 

Suggested Reading

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    Herkowitz HN, Garfin SR, Eismont FJ, Bel GR, Balderston RA. Rothman-Simeone The spine. 6th ed. Philadelphia, PA: Saunders; 2011Google Scholar
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    Khalessi AA, Oh BC, Wang MY. Medical management of ankylosing spondylitis. Neurosurg Focus. 2008;24(1):E4. Review. PubMed PMID: 18290742.
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    Kubiak EN, Moskovich R, Errico TJ, Di Cesare PE. Orthopaedic management of ankylosing spondylitis. J Am Acad Orthop Surg. 2005;13(4):267–78. PubMed PMID: 16112983.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Eren O. Kuris
    • 1
  1. 1.Department of Orthopaedic SurgeryWarren Alpert Medical School of Brown UniversityProvidenceUSA

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