Chemical Liposculpture of the Chin

  • Valerie D. CallenderEmail author
  • Jessica A. McCarrick


ATX-101, deoxycholic acid injection (DCA), is indicated for cosmetic reduction of moderate to severe submental fat. It works by inducing adipocytolysis and recruitment of neutrophils, macrophages, and fibroblasts, leading to long-lasting fat reduction and mild improvement in skin laxity through neocollagenesis. Procedure-specific side effects, which include submental alopecia, marginal mandibular nerve injury, and dysphagia, are both mild and transient. ATX-101 offers a pharmacologic, minimally invasive alternative to liposuction and other invasive surgical techniques in the treatment/reduction of undesired submental fat and improvement in submental profile.


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Callender Dermatology and Cosmetic CenterGlenn DaleUSA
  2. 2.Department of DermatologyHoward University HospitalWashingtonUSA

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